A nine-year-old boy contracted an often-deadly disease during a camping trip in July in northern Ontario.
The Canadian Medical Association Journal (CMAJ) detailed the boy’s battle with the Powassan virus, which officials believe he contracted from a tick bite.
Thankfully, he recovered despite becoming severely ill. The CMA said it was publishing the story in hopes of raising awareness of the virus to help speed up the diagnosis of patients in the future.
“Increased awareness of Powassan virus among clinicians in Canada will likely lead to increased identification of Powassan virus and other arthropod-borne infections, which should always be reported,” the CMAJ story said.
The youngster landed in hospital in July after suffering from severe neck stiffness, fever and a headache for about one day.
“Symptoms began one week after he attended a summer camping trip in northern Ontario,” the story in the CMA Journal reported.
“On arrival at the hospital, the patient was febrile (feverish) and appeared unwell, though he was hemodynamically stable, and the neurologic exam was normal at the time.”
The Magnetic resonance imaging (MRI) of the brain of the nine-year-old boy who contracted the Powassan virus during a northern Ontario camping trip in July. (Photo courtesy of the Canadian Medical Association Journal)
He had no rashes and doctors suspected that he was suffering from meningitis. That was eventually ruled out through testing, along with several other possible conditions.
“The patient remained persistently febrile with ongoing severe headache,” the story said.
“On the third day of hospital admission, the patient was transferred to our tertiary care hospital’s pediatric intensive care unit, because his level of consciousness was deteriorating.”
At that point, he couldn’t speak or respond to verbal commands and appeared to be in a coma. An MRI showed slowing brain activity, but no evidence of a brain seizure.
Brain swelling
More conditions – including Lyme disease – were ruled out. Samples were sent to Public Health Ontario, but results didn’t come back before he recovered enough to leave hospital.
He was given treatment antibiotics to address brain swelling, “with notable improvement in his level of consciousness within 24–48 hours,” the story said.
“We discontinued antibiotics after a total of five days once bacterial cultures were found to be negative. The patient was subsequently transferred to the inpatient pediatric ward for 10 days for rehabilitation related to a persistent left-sided weakness.”
Two months after he was discharged, “he had full neurologic recovery,” the story said.
“After discharge, Public Health Ontario notified us that serum antibodies to Powassan virus were detected.”
Powassan is a tick-borne flavivirus first discovered in 1958 in Powassan, Ont., after being isolated from the brain tissue of a child who died from the virus.
“Transmission to humans occurs predominantly via the bite of infected ticks … which become infected after feeding on deer, groundhogs, mice, squirrels or other rodents,” the story said.
“Research in animal models has suggested that Powassan virus can be transmitted within 15 minutes of tick attachment.”
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It’s a rare virus, with most cases occurring from April to November.
From 2004 to 2022, the U.S. reported 288 cases of Powassan virus infection. Of those, 25 per cent occurred in children and 92 per cent of those infected had to be hospitalized.
A total of 36 – or 13 per cent – of the patients died.
“Only 21 cases have been reported in Canada since 2017, but a lack of clinical recognition, and hence testing, may result in underestimation of the incidence,” the CMAJ story said.
“Most patients experience flu-like symptoms lasting a few days; however, some patients will develop neuroinvasive disease presenting with symptoms characteristic of viral encephalitis, including fever, headache and altered mental status.”
About 50 per cent of people who get the virus have long-term effects, “including headaches, altered mental status, and cognitive difficulties.”
Read the full CMAJ report here.