First-ever nasal spray for severe allergic reactions gets approval in U.S.

The data also showed that nasal spray offers the same results regarding seeking care following an anaphylaxis attack. Both the Epi-Pen and other auto injectables, as well as the nasal spray, require a person to seek emergency care after an allergic reaction. Because the spray is on an even keel with the injectable epinephrine, it is considered a secondary option for people who cannot handle needles.

Contraindications and side effects

The only difference between the two appears to be the administration, which could cause issues for some people with nasal conditions. For example, someone living with nasal polyps or those who have had nasal surgery may not benefit from Neffy since the absorption of the drug may not be sufficient.

Both methods of epinephrine administration have side effects as well. The EpiPen may induce paleness, dizziness, weakness, headaches, anxiety, fear, and restlessness. In contrast, the nasal spray can cause a person to develop side effects such as throat irritation, tingling in the nose, headache, nasal discomfort, and feeling jittery.

Introducing a new treatment for a reason

The EpiPen and other auto injectables work well to help someone experiencing a severe allergic reaction. The reason for this new administration method doesn’t have much bearing on how it works but rather the stress that can come along with administering a needle to someone who’s experiencing anaphylaxis alongside a severe fear of needles.

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